The Relationship of Serum Dehydroepiandrosterone and Its Sulfate to Subsequent Cancer of the Prostate1

نویسندگان

  • George W. Comstock
  • Gary B. Gordon
  • Ann W. Hsing
چکیده

Levels of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) in sera collected and frozen in J .were studied among 81 prostate cancer cases diagnosed in the following 12 years and 81 ageand race-matched controls. Although mean levels of DHEA were 1 1% lower among cases than controls and DHEA-S levels were 12% lower than among controls, no dose-response association was noted for either DHEA or DHEA-S. It seems unlikely that serum levels of DHEA or DHEA-S are important risk factors for prostate cancer.

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تاریخ انتشار 2005